藥物交互作用
Capreomycin + Pancuronium
嚴重程度: 嚴重
Capreomycin and Pancuronium: major interaction.
最後更新
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摘要
Capreomycin has neuromuscular blocking activity and can potentiate and prolong pancuronium paralysis. This can cause delayed recovery and respiratory depression or apnea.
用白話說明這項交互作用的意義
Capreomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Capreomycin has curare-like neuromuscular blocking action that adds to nondepolarizing blockade.
處置方式
Avoid combining if possible; otherwise reduce pancuronium dose, monitor with train-of-four and keep ventilatory support available through recovery.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pancuronium 的其他交互作用
常見問題
Can I take Capreomycin with Pancuronium?
MediHelp rates the interaction as major. Capreomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin has neuromuscular blocking activity and can potentiate and prolong pancuronium paralysis. This can cause delayed recovery and respiratory depression or apnea.
How serious is the interaction between Capreomycin and Pancuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining if possible; otherwise reduce pancuronium dose, monitor with train-of-four and keep ventilatory support available through recovery.
What other medicines interact with Pancuronium?
MediHelp also lists interactions of Pancuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Clindamycin. The full list is on the Pancuronium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
