藥物交互作用
Carbenoxolone + Torsemide
嚴重程度: 嚴重
Carbenoxolone and Torsemide: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Carbenoxolone has mineralocorticoid-like activity causing sodium and water retention and potassium loss. With torsemide, hypokalemia can be pronounced and the diuretic effect may be opposed.
用白話說明這項交互作用的意義
Carbenoxolone and Torsemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Carbenoxolone inhibits 11-beta-hydroxysteroid dehydrogenase, giving mineralocorticoid excess that adds to loop diuretic potassium wasting.
處置方式
Avoid the combination where possible. If used together, monitor serum potassium and blood pressure closely and replace potassium as required.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Torsemide 的其他交互作用
常見問題
Can I take Carbenoxolone with Torsemide?
MediHelp rates the interaction as major. Carbenoxolone and Torsemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carbenoxolone has mineralocorticoid-like activity causing sodium and water retention and potassium loss. With torsemide, hypokalemia can be pronounced and the diuretic effect may be opposed.
How serious is the interaction between Carbenoxolone and Torsemide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible. If used together, monitor serum potassium and blood pressure closely and replace potassium as required.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Chlorthalidone. The full list is on the Torsemide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
