藥物交互作用
Dexamethasone-tobramycin + Torsemide
嚴重程度: 嚴重
Dexamethasone-tobramycin and Torsemide: major interaction.
最後更新
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摘要
Loop diuretics combined with systemic aminoglycosides increase the risk of ototoxicity and nephrotoxicity, especially with volume depletion. This is relevant mainly with systemic tobramycin.
用白話說明這項交互作用的意義
Dexamethasone-tobramycin and Torsemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexamethasone-tobramycin belongs to Anti Bacterial; Torsemide belongs to Cardiovascular.
為什麼會發生
Additive ototoxic and nephrotoxic effects, with diuretic-induced volume depletion raising aminoglycoside exposure in the kidney and inner ear.
處置方式
Monitor renal function, tobramycin levels and hearing, keep the patient well hydrated, and avoid the combination if alternatives exist.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Dexamethasone-tobramycin 的其他交互作用
Torsemide 的其他交互作用
常見問題
Can I take Dexamethasone-tobramycin with Torsemide?
MediHelp rates the interaction as major. Dexamethasone-tobramycin and Torsemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Loop diuretics combined with systemic aminoglycosides increase the risk of ototoxicity and nephrotoxicity, especially with volume depletion. This is relevant mainly with systemic tobramycin.
How serious is the interaction between Dexamethasone-tobramycin and Torsemide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, tobramycin levels and hearing, keep the patient well hydrated, and avoid the combination if alternatives exist.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
