藥物交互作用
Ethacrynic acid + Torsemide
嚴重程度: 嚴重
Ethacrynic acid and Torsemide: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Two loop diuretics given together have additive effects on fluid and electrolyte loss, with a high risk of hypokalemia, hypomagnesemia, hypovolemia and ototoxicity. There is rarely a reason to combine them.
用白話說明這項交互作用的意義
Ethacrynic acid and Torsemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ethacrynic acid belongs to Cardiovascular; Torsemide belongs to Cardiovascular.
為什麼會發生
Both inhibit the Na-K-2Cl cotransporter in the thick ascending limb, producing additive diuresis and ototoxic potential.
處置方式
Avoid concurrent use; use a single loop diuretic at an adjusted dose, or add a thiazide if more diuresis is needed. If combined, monitor electrolytes, renal function and hearing.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Torsemide 的其他交互作用
Ethacrynic acid 的其他交互作用
常見問題
Can I take Ethacrynic acid with Torsemide?
MediHelp rates the interaction as major. Ethacrynic acid and Torsemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Two loop diuretics given together have additive effects on fluid and electrolyte loss, with a high risk of hypokalemia, hypomagnesemia, hypovolemia and ototoxicity. There is rarely a reason to combine them.
How serious is the interaction between Ethacrynic acid and Torsemide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; use a single loop diuretic at an adjusted dose, or add a thiazide if more diuresis is needed. If combined, monitor electrolytes, renal function and hearing.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
