藥物交互作用
Carbidopa-levodopa + Carbonyl iron
嚴重程度: 中度
Carbidopa-levodopa and Carbonyl iron: moderate interaction.
最後更新
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摘要
Oral iron can reduce the absorption of levodopa and carbidopa, which may lessen the antiparkinsonian effect and cause worsening motor symptoms or wearing-off.
用白話說明這項交互作用的意義
Carbidopa-levodopa and Carbonyl iron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbidopa-levodopa belongs to Central Nervous System; Carbonyl iron belongs to Miscellaneous.
為什麼會發生
Iron forms chelate complexes with levodopa and carbidopa in the gut, reducing their absorption.
處置方式
Separate oral iron from carbidopa-levodopa by at least 2 hours. Monitor motor response if iron therapy is started or stopped.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Carbidopa-levodopa 的其他交互作用
Carbonyl iron 的其他交互作用
常見問題
Can I take Carbidopa-levodopa with Carbonyl iron?
MediHelp rates the interaction as moderate. Carbidopa-levodopa and Carbonyl iron can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron can reduce the absorption of levodopa and carbidopa, which may lessen the antiparkinsonian effect and cause worsening motor symptoms or wearing-off.
How serious is the interaction between Carbidopa-levodopa and Carbonyl iron?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate oral iron from carbidopa-levodopa by at least 2 hours. Monitor motor response if iron therapy is started or stopped.
What other medicines interact with Carbidopa-levodopa?
MediHelp also lists interactions of Carbidopa-levodopa with, for example, Isocarboxazid, Phenelzine, Selegiline transdermal. The full list is on the Carbidopa-levodopa page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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