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藥物交互作用

Carvedilol + Theophylline

嚴重程度: 嚴重

Carvedilol and Theophylline: major interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Carvedilol is a nonselective beta-blocker and can cause bronchospasm that opposes theophylline's effect. It may also reduce theophylline clearance, raising levels and risk of toxicity.

用白話說明這項交互作用的意義

Carvedilol and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Carvedilol belongs to Cardiovascular; Theophylline belongs to Respiratory.

證據等級: Moderate

為什麼會發生

Beta-2 receptor antagonism opposes bronchodilation, with possible inhibition of theophylline metabolism.

處置方式

Avoid in patients with significant asthma or COPD; if used, monitor theophylline levels and respiratory function closely.

可向藥師詢問的問題

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Carvedilol 與 Theophylline 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Carvedilol with Theophylline?

MediHelp rates the interaction as major. Carvedilol and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carvedilol is a nonselective beta-blocker and can cause bronchospasm that opposes theophylline's effect. It may also reduce theophylline clearance, raising levels and risk of toxicity.

How serious is the interaction between Carvedilol and Theophylline?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with significant asthma or COPD; if used, monitor theophylline levels and respiratory function closely.

What other medicines interact with Theophylline?

MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.

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