藥物交互作用
Carvedilol + Umeclidinium-vilanterol
嚴重程度: 嚴重
Carvedilol and Umeclidinium-vilanterol: major interaction.
最後更新
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摘要
Carvedilol is a non-selective beta-blocker and can block the bronchodilating effect of vilanterol. It may provoke bronchospasm in patients with asthma or COPD.
用白話說明這項交互作用的意義
Carvedilol and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Carvedilol belongs to Cardiovascular; Umeclidinium-vilanterol belongs to Respiratory.
為什麼會發生
Pharmacodynamic antagonism through beta-2 receptor blockade.
處置方式
Prefer a beta-1 selective blocker such as bisoprolol or metoprolol where a beta-blocker is needed. Monitor lung function and symptoms if carvedilol is continued.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Umeclidinium-vilanterol 的其他交互作用
Carvedilol 的其他交互作用
常見問題
Can I take Carvedilol with Umeclidinium-vilanterol?
MediHelp rates the interaction as major. Carvedilol and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carvedilol is a non-selective beta-blocker and can block the bronchodilating effect of vilanterol. It may provoke bronchospasm in patients with asthma or COPD.
How serious is the interaction between Carvedilol and Umeclidinium-vilanterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer a beta-1 selective blocker such as bisoprolol or metoprolol where a beta-blocker is needed. Monitor lung function and symptoms if carvedilol is continued.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。