藥物交互作用
Arformoterol + Umeclidinium-vilanterol
嚴重程度: 嚴重
Arformoterol and Umeclidinium-vilanterol: major interaction.
最後更新
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摘要
Both drugs are long-acting beta-2 agonists, so using them together duplicates therapy. This increases the risk of tachycardia, arrhythmia, tremor, hypokalemia and QT prolongation without added benefit.
用白話說明這項交互作用的意義
Arformoterol and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arformoterol belongs to Respiratory; Umeclidinium-vilanterol belongs to Respiratory.
為什麼會發生
Duplicate beta-2 agonist pharmacology with additive cardiovascular and metabolic effects.
處置方式
Avoid concurrent use of two long-acting beta-agonists and use only one. Monitor heart rate and potassium if a switch is under way.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Umeclidinium-vilanterol 的其他交互作用
Arformoterol 的其他交互作用
常見問題
Can I take Arformoterol with Umeclidinium-vilanterol?
MediHelp rates the interaction as major. Arformoterol and Umeclidinium-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are long-acting beta-2 agonists, so using them together duplicates therapy. This increases the risk of tachycardia, arrhythmia, tremor, hypokalemia and QT prolongation without added benefit.
How serious is the interaction between Arformoterol and Umeclidinium-vilanterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two long-acting beta-agonists and use only one. Monitor heart rate and potassium if a switch is under way.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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