藥物交互作用
Cefadroxil + Plazomicin
嚴重程度: 中度
Cefadroxil and Plazomicin: moderate interaction.
最後更新
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摘要
Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and its labeling advises caution with other nephrotoxic agents. Cephalosporins have been reported to occasionally add to renal injury. Both are renally eliminated, so renal decline raises exposure.
用白話說明這項交互作用的意義
Cefadroxil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefadroxil belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
為什麼會發生
Additive nephrotoxicity with reduced renal clearance of both drugs as kidney function declines.
處置方式
Monitor serum creatinine and plazomicin levels per labeling, and adjust doses to renal function. Monitor for hearing or vestibular symptoms.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefadroxil 的其他交互作用
Plazomicin 的其他交互作用
常見問題
Can I take Cefadroxil with Plazomicin?
MediHelp rates the interaction as moderate. Cefadroxil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and its labeling advises caution with other nephrotoxic agents. Cephalosporins have been reported to occasionally add to renal injury. Both are renally eliminated, so renal decline raises exposure.
How serious is the interaction between Cefadroxil and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin levels per labeling, and adjust doses to renal function. Monitor for hearing or vestibular symptoms.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
