藥物交互作用
Cefalexin + Plazomicin
嚴重程度: 中度
Cefalexin and Plazomicin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Plazomicin is an aminoglycoside with labeled risks of nephrotoxicity and ototoxicity. Other agents that can impair renal function, including cephalosporins in some reports, may add to kidney injury and raise plazomicin exposure.
用白話說明這項交互作用的意義
Cefalexin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefalexin belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
為什麼會發生
Additive nephrotoxic potential, with reduced renal clearance increasing aminoglycoside accumulation and ototoxicity.
處置方式
Monitor serum creatinine and plazomicin concentrations, and adjust dosing to renal function per labeling. Watch for hearing loss, tinnitus or vestibular symptoms.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefalexin 的其他交互作用
Plazomicin 的其他交互作用
常見問題
Can I take Cefalexin with Plazomicin?
MediHelp rates the interaction as moderate. Cefalexin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with labeled risks of nephrotoxicity and ototoxicity. Other agents that can impair renal function, including cephalosporins in some reports, may add to kidney injury and raise plazomicin exposure.
How serious is the interaction between Cefalexin and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations, and adjust dosing to renal function per labeling. Watch for hearing loss, tinnitus or vestibular symptoms.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
