藥物交互作用
Cefazolin + Cholera vaccine
嚴重程度: 中度
Cefazolin and Cholera vaccine: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The oral live attenuated cholera vaccine can be inactivated by active antibiotics, reducing immune response. A single perioperative cefazolin dose is less likely to matter but the labeling advice still applies.
用白話說明這項交互作用的意義
Cefazolin and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity against the live attenuated vaccine strain reduces its replication and immunogenicity.
處置方式
Avoid vaccination within 14 days of systemic antibiotic use, as per labeling; defer the vaccine until the course is completed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefazolin 的其他交互作用
常見問題
Can I take Cefazolin with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefazolin and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine can be inactivated by active antibiotics, reducing immune response. A single perioperative cefazolin dose is less likely to matter but the labeling advice still applies.
How serious is the interaction between Cefazolin and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vaccination within 14 days of systemic antibiotic use, as per labeling; defer the vaccine until the course is completed.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Dexamethasone-tobramycin. The full list is on the Cefazolin page.
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