藥物交互作用
Cefotaxime + Cholera vaccine
嚴重程度: 中度
Cefotaxime and Cholera vaccine: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response.
用白話說明這項交互作用的意義
Cefotaxime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity may inhibit replication of the live attenuated vaccine strain, lowering immunogenicity.
處置方式
Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefotaxime 的其他交互作用
常見問題
Can I take Cefotaxime with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefotaxime and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response.
How serious is the interaction between Cefotaxime and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
What other medicines interact with Cefotaxime?
MediHelp also lists interactions of Cefotaxime with, for example, Typhoid vaccine live, Amikacin, Dexamethasone-tobramycin. The full list is on the Cefotaxime page.
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