藥物交互作用
Cefotaxime + Microbiota
嚴重程度: 中度
Cefotaxime and Microbiota: moderate interaction.
最後更新
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摘要
Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
用白話說明這項交互作用的意義
Cefotaxime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibacterial activity against the live bacterial components of the product reduces colonization (pharmacodynamic antagonism).
處置方式
Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefotaxime 的其他交互作用
常見問題
Can I take Cefotaxime with Microbiota?
MediHelp rates the interaction as moderate. Cefotaxime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
How serious is the interaction between Cefotaxime and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
What other medicines interact with Cefotaxime?
MediHelp also lists interactions of Cefotaxime with, for example, Typhoid vaccine live, Amikacin, Cholera vaccine. The full list is on the Cefotaxime page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
