藥物交互作用
Cefotaxime + Dexamethasone-tobramycin
嚴重程度: 中度
Cefotaxime and Dexamethasone-tobramycin: moderate interaction.
最後更新
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摘要
Cefotaxime with an aminoglycoside has been linked to additive kidney injury in some reports, particularly in patients with renal impairment or volume depletion.
用白話說明這項交互作用的意義
Cefotaxime and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefotaxime belongs to Anti Bacterial; Dexamethasone-tobramycin belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity; mechanism not firmly established.
處置方式
Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Dexamethasone-tobramycin 的其他交互作用
Cefotaxime 的其他交互作用
常見問題
Can I take Cefotaxime with Dexamethasone-tobramycin?
MediHelp rates the interaction as moderate. Cefotaxime and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefotaxime with an aminoglycoside has been linked to additive kidney injury in some reports, particularly in patients with renal impairment or volume depletion.
How serious is the interaction between Cefotaxime and Dexamethasone-tobramycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
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