藥物交互作用
Cefpodoxime + Famotidine
嚴重程度: 中度
Cefpodoxime and Famotidine: moderate interaction.
最後更新
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摘要
Cefpodoxime proxetil needs gastric acid for dissolution and absorption, so H2 blockers lower its systemic exposure. This can reduce antibacterial efficacy.
用白話說明這項交互作用的意義
Cefpodoxime and Famotidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpodoxime belongs to Anti Bacterial; Famotidine belongs to Gastrointestinal Tract.
為什麼會發生
Elevated gastric pH reduces dissolution and absorption of cefpodoxime proxetil.
處置方式
Avoid the combination if possible, or choose an antibiotic not dependent on gastric acidity. Monitor the clinical response to treatment.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Famotidine 的其他交互作用
Cefpodoxime 的其他交互作用
常見問題
Can I take Cefpodoxime with Famotidine?
MediHelp rates the interaction as moderate. Cefpodoxime and Famotidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefpodoxime proxetil needs gastric acid for dissolution and absorption, so H2 blockers lower its systemic exposure. This can reduce antibacterial efficacy.
How serious is the interaction between Cefpodoxime and Famotidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if possible, or choose an antibiotic not dependent on gastric acidity. Monitor the clinical response to treatment.
What other medicines interact with Famotidine?
MediHelp also lists interactions of Famotidine with, for example, Atazanavir, Dasatinib, Infigratinib. The full list is on the Famotidine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
