藥物交互作用
Cefuroxime + Sodium bicarbonate
嚴重程度: 中度
Cefuroxime and Sodium bicarbonate: moderate interaction.
最後更新
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摘要
Oral cefuroxime axetil absorption is better in an acidic stomach, and antacids such as sodium bicarbonate raise gastric pH. This can reduce cefuroxime exposure and might weaken the antibacterial effect.
用白話說明這項交互作用的意義
Cefuroxime and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefuroxime belongs to Anti Bacterial; Sodium bicarbonate belongs to Gastrointestinal Tract.
為什麼會發生
Higher gastric pH reduces dissolution and absorption of cefuroxime axetil.
處置方式
Separate sodium bicarbonate from oral cefuroxime axetil by about 2 hours, taking cefuroxime with food. Use an alternative antibiotic if acid suppression cannot be avoided in a serious infection.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefuroxime 的其他交互作用
Sodium bicarbonate 的其他交互作用
常見問題
Can I take Cefuroxime with Sodium bicarbonate?
MediHelp rates the interaction as moderate. Cefuroxime and Sodium bicarbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral cefuroxime axetil absorption is better in an acidic stomach, and antacids such as sodium bicarbonate raise gastric pH. This can reduce cefuroxime exposure and might weaken the antibacterial effect.
How serious is the interaction between Cefuroxime and Sodium bicarbonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sodium bicarbonate from oral cefuroxime axetil by about 2 hours, taking cefuroxime with food. Use an alternative antibiotic if acid suppression cannot be avoided in a serious infection.
What other medicines interact with Cefuroxime?
MediHelp also lists interactions of Cefuroxime with, for example, Aluminum hydroxide, Amikacin, Bcg vaccine live. The full list is on the Cefuroxime page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
