藥物交互作用
Celecoxib + Ketorolac
嚴重程度: 禁忌併用
Celecoxib and Ketorolac: contraindicated interaction.
最後更新
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摘要
Ketorolac is contraindicated with other NSAIDs, and celecoxib adds cyclo-oxygenase inhibition on top of ketorolac's. Gastrointestinal bleeding, renal injury and cardiovascular events are more likely without additional analgesic benefit.
用白話說明這項交互作用的意義
Celecoxib and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Celecoxib belongs to Musculoskeletal; Ketorolac belongs to Musculoskeletal.
為什麼會發生
Additive COX inhibition causing gastrointestinal, renal and platelet effects
處置方式
Do not use together; use one NSAID only, or add paracetamol or an opioid for additional analgesia.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ketorolac 的其他交互作用
Celecoxib 的其他交互作用
常見問題
Can I take Celecoxib with Ketorolac?
MediHelp rates the interaction as contraindicated. Celecoxib and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac is contraindicated with other NSAIDs, and celecoxib adds cyclo-oxygenase inhibition on top of ketorolac's. Gastrointestinal bleeding, renal injury and cardiovascular events are more likely without additional analgesic benefit.
How serious is the interaction between Celecoxib and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; use one NSAID only, or add paracetamol or an opioid for additional analgesia.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
