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藥物交互作用

Cimetidine + Vitamin B12

嚴重程度: 輕微

Cimetidine and Vitamin B12: minor interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Cimetidine reduces gastric acid, which lowers release of B12 from food proteins and may lower absorption with long-term use. Absorption of crystalline oral B12 is less affected, so clinical deficiency is uncommon.

用白話說明這項交互作用的意義

Cimetidine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cimetidine belongs to Gastrointestinal Tract; Vitamin B12 belongs to Gastrointestinal Tract.

證據等級: Moderate

為什麼會發生

Reduced gastric acid secretion impairs liberation of protein-bound dietary B12.

處置方式

Monitor B12 status in long-term users, especially older adults or those with other risk factors. Supplement if levels are low.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Cimetidine 與 Vitamin B12 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Cimetidine with Vitamin B12?

MediHelp rates the interaction as minor. Cimetidine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cimetidine reduces gastric acid, which lowers release of B12 from food proteins and may lower absorption with long-term use. Absorption of crystalline oral B12 is less affected, so clinical deficiency is uncommon.

How serious is the interaction between Cimetidine and Vitamin B12?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor B12 status in long-term users, especially older adults or those with other risk factors. Supplement if levels are low.

What other medicines interact with Vitamin B12?

MediHelp also lists interactions of Vitamin B12 with, for example, Chloramphenicol, Dichlorphenamide, Metformin. The full list is on the Vitamin B12 page.

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