藥物交互作用
Ciprofloxacin + Gliclazide
嚴重程度: 嚴重
Ciprofloxacin and Gliclazide: major interaction.
最後更新
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摘要
Fluoroquinolones such as ciprofloxacin can cause both severe hypoglycemia and hyperglycemia, especially in patients taking sulfonylureas. Older patients and those with renal impairment are at greatest risk.
用白話說明這項交互作用的意義
Ciprofloxacin and Gliclazide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Gliclazide belongs to Endocrine.
為什麼會發生
Fluoroquinolones alter pancreatic beta-cell insulin release, adding to sulfonylurea-induced insulin secretion; CYP2C9 inhibition may also contribute.
處置方式
Monitor blood glucose closely during the antibiotic course and warn the patient about hypoglycemia symptoms. Stop the fluoroquinolone and treat if significant glucose disturbance occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Gliclazide 的其他交互作用
Ciprofloxacin 的其他交互作用
常見問題
Can I take Ciprofloxacin with Gliclazide?
MediHelp rates the interaction as major. Ciprofloxacin and Gliclazide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fluoroquinolones such as ciprofloxacin can cause both severe hypoglycemia and hyperglycemia, especially in patients taking sulfonylureas. Older patients and those with renal impairment are at greatest risk.
How serious is the interaction between Ciprofloxacin and Gliclazide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely during the antibiotic course and warn the patient about hypoglycemia symptoms. Stop the fluoroquinolone and treat if significant glucose disturbance occurs.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Clarithromycin, Disopyramide, Fluconazole. The full list is on the Gliclazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
