藥物交互作用
Cisapride + Valbenazine
嚴重程度: 嚴重
Cisapride and Valbenazine: major interaction.
最後更新
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摘要
Valbenazine can prolong the QT interval, particularly at higher exposures, and cisapride is a well-known QT-prolonging drug. Combined use may raise the risk of torsades de pointes.
用白話說明這項交互作用的意義
Cisapride and Valbenazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cisapride belongs to Gastrointestinal Tract; Valbenazine belongs to Central Nervous System.
為什麼會發生
Additive QT interval prolongation.
處置方式
Avoid if possible; otherwise obtain an ECG, correct electrolytes and monitor for arrhythmia symptoms.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cisapride 的其他交互作用
Valbenazine 的其他交互作用
常見問題
Can I take Cisapride with Valbenazine?
MediHelp rates the interaction as major. Cisapride and Valbenazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valbenazine can prolong the QT interval, particularly at higher exposures, and cisapride is a well-known QT-prolonging drug. Combined use may raise the risk of torsades de pointes.
How serious is the interaction between Cisapride and Valbenazine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise obtain an ECG, correct electrolytes and monitor for arrhythmia symptoms.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
