藥物交互作用
Amiodarone + Valbenazine
嚴重程度: 嚴重
Amiodarone and Valbenazine: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both agents can prolong the QT interval, which may increase the risk of torsades de pointes. The risk is greater with other risk factors for arrhythmia.
用白話說明這項交互作用的意義
Amiodarone and Valbenazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amiodarone belongs to Cardiovascular; Valbenazine belongs to Central Nervous System.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Obtain a baseline ECG and correct electrolytes. Monitor QTc and consider an alternative to one agent if QTc becomes prolonged.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Amiodarone 的其他交互作用
Valbenazine 的其他交互作用
常見問題
Can I take Amiodarone with Valbenazine?
MediHelp rates the interaction as major. Amiodarone and Valbenazine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents can prolong the QT interval, which may increase the risk of torsades de pointes. The risk is greater with other risk factors for arrhythmia.
How serious is the interaction between Amiodarone and Valbenazine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct electrolytes. Monitor QTc and consider an alternative to one agent if QTc becomes prolonged.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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