藥物交互作用
Clemastine + Methohexital
嚴重程度: 嚴重
Clemastine and Methohexital: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Methohexital is a short-acting barbiturate anesthetic and sedating antihistamines may deepen or prolong sedation. Respiratory depression and hypotension are possible during procedural use.
用白話說明這項交互作用的意義
Clemastine and Methohexital can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Clemastine belongs to Respiratory; Methohexital belongs to Central Nervous System.
為什麼會發生
Additive CNS and respiratory depression.
處置方式
Titrate methohexital carefully and monitor respiration, oxygenation and blood pressure continuously. Make sure the anesthesia team knows about recent clemastine use.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Clemastine 的其他交互作用
Methohexital 的其他交互作用
常見問題
Can I take Clemastine with Methohexital?
MediHelp rates the interaction as major. Clemastine and Methohexital can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Methohexital is a short-acting barbiturate anesthetic and sedating antihistamines may deepen or prolong sedation. Respiratory depression and hypotension are possible during procedural use.
How serious is the interaction between Clemastine and Methohexital?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate methohexital carefully and monitor respiration, oxygenation and blood pressure continuously. Make sure the anesthesia team knows about recent clemastine use.
What other medicines interact with Clemastine?
MediHelp also lists interactions of Clemastine with, for example, Alfentanil, Benzhydrocodone / acetaminophen, Buprenorphine buccal. The full list is on the Clemastine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
