藥物交互作用
Clindamycin + Vecuronium
嚴重程度: 嚴重
Clindamycin and Vecuronium: major interaction.
最後更新
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摘要
Clindamycin has intrinsic neuromuscular blocking activity and can deepen and prolong paralysis from vecuronium. Recovery of spontaneous breathing may be delayed.
用白話說明這項交互作用的意義
Clindamycin and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Clindamycin belongs to Anti Bacterial; Vecuronium belongs to Musculoskeletal.
為什麼會發生
Additive neuromuscular blockade through presynaptic and postsynaptic inhibition of transmission by clindamycin.
處置方式
Monitor train-of-four and titrate vecuronium to effect. Ensure full recovery of neuromuscular function before extubation.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Vecuronium 的其他交互作用
Clindamycin 的其他交互作用
常見問題
Can I take Clindamycin with Vecuronium?
MediHelp rates the interaction as major. Clindamycin and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Clindamycin has intrinsic neuromuscular blocking activity and can deepen and prolong paralysis from vecuronium. Recovery of spontaneous breathing may be delayed.
How serious is the interaction between Clindamycin and Vecuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor train-of-four and titrate vecuronium to effect. Ensure full recovery of neuromuscular function before extubation.
What other medicines interact with Vecuronium?
MediHelp also lists interactions of Vecuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Vecuronium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
