藥物交互作用
Cyclosporine + Entecavir
嚴重程度: 中度
Cyclosporine and Entecavir: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Cyclosporine can reduce renal function, which may increase entecavir exposure because entecavir is renally eliminated. The effect is usually modest, though the combination is common in transplant patients.
用白話說明這項交互作用的意義
Cyclosporine and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Cyclosporine-related reduction in glomerular filtration may decrease renal clearance of entecavir.
處置方式
Monitor renal function regularly and adjust the entecavir dose or interval according to creatinine clearance.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Entecavir 的其他交互作用
常見問題
Can I take Cyclosporine with Entecavir?
MediHelp rates the interaction as moderate. Cyclosporine and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine can reduce renal function, which may increase entecavir exposure because entecavir is renally eliminated. The effect is usually modest, though the combination is common in transplant patients.
How serious is the interaction between Cyclosporine and Entecavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function regularly and adjust the entecavir dose or interval according to creatinine clearance.
What other medicines interact with Entecavir?
MediHelp also lists interactions of Entecavir with, for example, Alogliptin-metformin, Canagliflozin-metformin, Cidofovir. The full list is on the Entecavir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。