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藥物交互作用

Cyclosporine + Entecavir

嚴重程度: 中度

Cyclosporine and Entecavir: moderate interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Cyclosporine can reduce renal function, which may increase entecavir exposure because entecavir is renally eliminated. The effect is usually modest, though the combination is common in transplant patients.

用白話說明這項交互作用的意義

Cyclosporine and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Low

為什麼會發生

Cyclosporine-related reduction in glomerular filtration may decrease renal clearance of entecavir.

處置方式

Monitor renal function regularly and adjust the entecavir dose or interval according to creatinine clearance.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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建立帳號並開始 Pro+ 試用,即可解鎖 Cyclosporine 與 Entecavir 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Cyclosporine with Entecavir?

MediHelp rates the interaction as moderate. Cyclosporine and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclosporine can reduce renal function, which may increase entecavir exposure because entecavir is renally eliminated. The effect is usually modest, though the combination is common in transplant patients.

How serious is the interaction between Cyclosporine and Entecavir?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function regularly and adjust the entecavir dose or interval according to creatinine clearance.

What other medicines interact with Entecavir?

MediHelp also lists interactions of Entecavir with, for example, Alogliptin-metformin, Canagliflozin-metformin, Cidofovir. The full list is on the Entecavir page.

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