藥物交互作用
Cidofovir + Entecavir
嚴重程度: 中度
Cidofovir and Entecavir: moderate interaction.
最後更新
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摘要
Both drugs are eliminated by the kidney including active tubular secretion, so they may raise each other's levels. Cidofovir's nephrotoxicity could further reduce entecavir clearance. The practical significance is uncertain.
用白話說明這項交互作用的意義
Cidofovir and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cidofovir belongs to Anti Virals; Entecavir belongs to Anti Virals.
為什麼會發生
Competition for renal tubular secretion and cidofovir-related reduction in renal function.
處置方式
Monitor renal function and adjust the entecavir dose according to creatinine clearance if renal function worsens.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cidofovir 的其他交互作用
Entecavir 的其他交互作用
常見問題
Can I take Cidofovir with Entecavir?
MediHelp rates the interaction as moderate. Cidofovir and Entecavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are eliminated by the kidney including active tubular secretion, so they may raise each other's levels. Cidofovir's nephrotoxicity could further reduce entecavir clearance. The practical significance is uncertain.
How serious is the interaction between Cidofovir and Entecavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and adjust the entecavir dose according to creatinine clearance if renal function worsens.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。