藥物交互作用
Daunorubicin + Olaparib
嚴重程度: 嚴重
Daunorubicin and Olaparib: major interaction.
最後更新
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摘要
Both drugs cause bone marrow suppression, so combination can cause deeper and longer-lasting cytopenias. This raises the risk of infection, bleeding and anemia.
用白話說明這項交互作用的意義
Daunorubicin and Olaparib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Daunorubicin belongs to Oncology; Olaparib belongs to Oncology.
為什麼會發生
Additive myelosuppression from DNA damage by daunorubicin and PARP inhibition by olaparib.
處置方式
Monitor complete blood counts frequently and reduce doses or delay cycles for severe cytopenias.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Daunorubicin 的其他交互作用
Olaparib 的其他交互作用
常見問題
Can I take Daunorubicin with Olaparib?
MediHelp rates the interaction as major. Daunorubicin and Olaparib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs cause bone marrow suppression, so combination can cause deeper and longer-lasting cytopenias. This raises the risk of infection, bleeding and anemia.
How serious is the interaction between Daunorubicin and Olaparib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts frequently and reduce doses or delay cycles for severe cytopenias.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclosporine. The full list is on the Daunorubicin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
