藥物交互作用
Deflazacort + Etravirine
嚴重程度: 嚴重
Deflazacort and Etravirine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Etravirine is a CYP3A4 inducer and may lower exposure to deflazacort's active metabolite. Reduced corticosteroid efficacy may result.
用白話說明這項交互作用的意義
Deflazacort and Etravirine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deflazacort belongs to Miscellaneous; Etravirine belongs to Anti Virals.
為什麼會發生
Etravirine induces CYP3A4, increasing clearance of deflazacort's active metabolite.
處置方式
Avoid concomitant use where possible. If it cannot be avoided, monitor for loss of efficacy and consider an alternative corticosteroid or dose adjustment.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Deflazacort 的其他交互作用
- Adenovirus types 4 and 7 live + Deflazacort 禁忌併用
- Bcg vaccine live + Deflazacort 禁忌併用
- Deflazacort + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Deflazacort + Measles mumps and rubella vaccine 禁忌併用
- Deflazacort + Measles mumps and rubella vaccine live 禁忌併用
- Deflazacort + Measles mumps rubella and varicella vaccine live 禁忌併用
Etravirine 的其他交互作用
常見問題
Can I take Deflazacort with Etravirine?
MediHelp rates the interaction as major. Deflazacort and Etravirine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etravirine is a CYP3A4 inducer and may lower exposure to deflazacort's active metabolite. Reduced corticosteroid efficacy may result.
How serious is the interaction between Deflazacort and Etravirine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concomitant use where possible. If it cannot be avoided, monitor for loss of efficacy and consider an alternative corticosteroid or dose adjustment.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
