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藥物交互作用

Deflazacort + Lubiprostone

嚴重程度: 輕微

Deflazacort and Lubiprostone: minor interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Lubiprostone can cause diarrhea and corticosteroids promote renal potassium loss, so potassium depletion may be additive. Clinically significant hypokalemia is more likely with prolonged use or other potassium-lowering drugs.

用白話說明這項交互作用的意義

Deflazacort and Lubiprostone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Deflazacort belongs to Miscellaneous; Lubiprostone belongs to Gastrointestinal Tract.

證據等級: Low

為什麼會發生

Additive potassium loss via renal excretion (corticosteroid) and gastrointestinal fluid loss (lubiprostone-induced diarrhea).

處置方式

Monitor serum potassium if diarrhea develops or therapy is prolonged, and replace as needed.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Deflazacort 與 Lubiprostone 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

在網頁版免費試用 Pro+ 14 天,無需信用卡。

常見問題

Can I take Deflazacort with Lubiprostone?

MediHelp rates the interaction as minor. Deflazacort and Lubiprostone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lubiprostone can cause diarrhea and corticosteroids promote renal potassium loss, so potassium depletion may be additive. Clinically significant hypokalemia is more likely with prolonged use or other potassium-lowering drugs.

How serious is the interaction between Deflazacort and Lubiprostone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if diarrhea develops or therapy is prolonged, and replace as needed.

What other medicines interact with Deflazacort?

MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.

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