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藥物交互作用

Delafloxacin + Didanosine

嚴重程度: 中度

Delafloxacin and Didanosine: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.

用白話說明這項交互作用的意義

Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Delafloxacin belongs to Anti Bacterial; Didanosine belongs to Anti Virals.

證據等級: Moderate

為什麼會發生

Chelation of delafloxacin by the polyvalent cations in buffered didanosine reduces absorption.

處置方式

Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Delafloxacin with Didanosine?

MediHelp rates the interaction as moderate. Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.

How serious is the interaction between Delafloxacin and Didanosine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.

What other medicines interact with Delafloxacin?

MediHelp also lists interactions of Delafloxacin with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Delafloxacin page.

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