藥物交互作用
Delamanid + Moxifloxacin
嚴重程度: 嚴重
Delamanid and Moxifloxacin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Both drugs prolong the QT interval, so the combination increases the risk of torsades de pointes and serious arrhythmia.
用白話說明這項交互作用的意義
Delamanid and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Delamanid belongs to Anti Bacterial; Moxifloxacin belongs to Anti Bacterial.
為什麼會發生
Additive QT prolongation through cardiac repolarization effects.
處置方式
Avoid the combination when alternatives exist. If unavoidable, perform frequent ECG monitoring and correct potassium, magnesium and calcium.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Delamanid 的其他交互作用
Moxifloxacin 的其他交互作用
常見問題
Can I take Delamanid with Moxifloxacin?
MediHelp rates the interaction as major. Delamanid and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs prolong the QT interval, so the combination increases the risk of torsades de pointes and serious arrhythmia.
How serious is the interaction between Delamanid and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination when alternatives exist. If unavoidable, perform frequent ECG monitoring and correct potassium, magnesium and calcium.
What other medicines interact with Delamanid?
MediHelp also lists interactions of Delamanid with, for example, Carbamazepine, Rifampicin, Ritonavir. The full list is on the Delamanid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
