藥物交互作用
Dexmethylphenidate + Rasagiline
嚴重程度: 禁忌併用
Dexmethylphenidate and Rasagiline: contraindicated interaction.
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摘要
Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
用白話說明這項交互作用的意義
Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.
為什麼會發生
Dexmethylphenidate increases synaptic catecholamines and MAO inhibition prevents their breakdown, causing additive pressor effects.
處置方式
Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Rasagiline 的其他交互作用
Dexmethylphenidate 的其他交互作用
常見問題
Can I take Dexmethylphenidate with Rasagiline?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
How serious is the interaction between Dexmethylphenidate and Rasagiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
What other medicines interact with Rasagiline?
MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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