藥物交互作用
Edoxaban + Ketorolac
嚴重程度: 禁忌併用
Edoxaban and Ketorolac: contraindicated interaction.
最後更新
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摘要
Ketorolac impairs platelet function and damages gastric mucosa while edoxaban is an anticoagulant, so major bleeding risk is considerably increased. Ketorolac labeling contraindicates its use in patients at risk of bleeding and with anticoagulants.
用白話說明這項交互作用的意義
Edoxaban and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Edoxaban belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
為什麼會發生
Additive hemostatic impairment from NSAID platelet inhibition and factor Xa inhibition.
處置方式
Avoid ketorolac with edoxaban and use a non-NSAID analgesic; if exposure occurs, monitor for bleeding and hemoglobin changes.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ketorolac 的其他交互作用
Edoxaban 的其他交互作用
常見問題
Can I take Edoxaban with Ketorolac?
MediHelp rates the interaction as contraindicated. Edoxaban and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac impairs platelet function and damages gastric mucosa while edoxaban is an anticoagulant, so major bleeding risk is considerably increased. Ketorolac labeling contraindicates its use in patients at risk of bleeding and with anticoagulants.
How serious is the interaction between Edoxaban and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac with edoxaban and use a non-NSAID analgesic; if exposure occurs, monitor for bleeding and hemoglobin changes.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
