藥物交互作用
Elvitegravir / cobicistat / emtricitabine / tenofovir df + Zidovudine
嚴重程度: 禁忌併用
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Zidovudine: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
This fixed-dose product is a complete HIV regimen and is not intended for use with other antiretrovirals. Adding zidovudine duplicates the nucleoside backbone, adds hematologic toxicity, and offers no proven benefit.
用白話說明這項交互作用的意義
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Zidovudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Therapeutic duplication of nucleoside reverse transcriptase inhibitors, with additive toxicity and no established benefit.
處置方式
Do not co-administer; use the complete regimen alone or build a different regimen. Discontinue zidovudine if the single-tablet regimen is chosen.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Zidovudine 的其他交互作用
常見問題
Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Zidovudine?
MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Zidovudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This fixed-dose product is a complete HIV regimen and is not intended for use with other antiretrovirals. Adding zidovudine duplicates the nucleoside backbone, adds hematologic toxicity, and offers no proven benefit.
How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Zidovudine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; use the complete regimen alone or build a different regimen. Discontinue zidovudine if the single-tablet regimen is chosen.
What other medicines interact with Zidovudine?
MediHelp also lists interactions of Zidovudine with, for example, Stavudine, Atidarsagene autotemcel, Betibeglogene autotemcel. The full list is on the Zidovudine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
