藥物交互作用
Ergoloid mesylates + Rizatriptan
嚴重程度: 禁忌併用
Ergoloid mesylates and Rizatriptan: contraindicated interaction.
最後更新
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摘要
Rizatriptan constricts cranial and other vessels, and ergoloid has some ergot-derived receptor activity, so additive vasoconstriction is possible. The vasoconstrictor effect of ergoloid is weak, but the class warning still applies.
用白話說明這項交互作用的意義
Ergoloid mesylates and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Additive vasoconstriction through serotonin receptor agonism and ergot-derived receptor effects.
處置方式
Avoid combining and separate by at least 24 hours. Review whether ergoloid therapy is needed.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Rizatriptan 的其他交互作用
常見問題
Can I take Ergoloid mesylates with Rizatriptan?
MediHelp rates the interaction as contraindicated. Ergoloid mesylates and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rizatriptan constricts cranial and other vessels, and ergoloid has some ergot-derived receptor activity, so additive vasoconstriction is possible. The vasoconstrictor effect of ergoloid is weak, but the class warning still applies.
How serious is the interaction between Ergoloid mesylates and Rizatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining and separate by at least 24 hours. Review whether ergoloid therapy is needed.
What other medicines interact with Rizatriptan?
MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Rizatriptan page.
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