藥物交互作用
Ergotamine + Rizatriptan
嚴重程度: 禁忌併用
Ergotamine and Rizatriptan: contraindicated interaction.
最後更新
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摘要
Ergotamine and rizatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
用白話說明這項交互作用的意義
Ergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ergotamine belongs to Central Nervous System; Rizatriptan belongs to Central Nervous System.
為什麼會發生
Additive vasoconstriction through serotonin receptors
處置方式
Do not administer within 24 hours of each other.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Rizatriptan 的其他交互作用
Ergotamine 的其他交互作用
常見問題
Can I take Ergotamine with Rizatriptan?
MediHelp rates the interaction as contraindicated. Ergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and rizatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
How serious is the interaction between Ergotamine and Rizatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer within 24 hours of each other.
What other medicines interact with Rizatriptan?
MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Rizatriptan page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。