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藥物交互作用

Ergotamine + Rizatriptan

嚴重程度: 禁忌併用

Ergotamine and Rizatriptan: contraindicated interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Ergotamine and rizatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.

用白話說明這項交互作用的意義

Ergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Ergotamine belongs to Central Nervous System; Rizatriptan belongs to Central Nervous System.

證據等級: High

為什麼會發生

Additive vasoconstriction through serotonin receptors

處置方式

Do not administer within 24 hours of each other.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Ergotamine 與 Rizatriptan 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Ergotamine with Rizatriptan?

MediHelp rates the interaction as contraindicated. Ergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and rizatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.

How serious is the interaction between Ergotamine and Rizatriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer within 24 hours of each other.

What other medicines interact with Rizatriptan?

MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Rizatriptan page.

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