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藥物交互作用

Frovatriptan + Rizatriptan

嚴重程度: 禁忌併用

Frovatriptan and Rizatriptan: contraindicated interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Frovatriptan and rizatriptan are both 5-HT1B/1D agonists that constrict cranial and coronary vessels. Taken close together, the vasoconstriction is additive and may cause coronary or peripheral vasospasm.

用白話說明這項交互作用的意義

Frovatriptan and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Frovatriptan belongs to Central Nervous System; Rizatriptan belongs to Central Nervous System.

證據等級: Moderate

為什麼會發生

Additive 5-HT1B/1D-mediated vasoconstriction

處置方式

Do not use frovatriptan and rizatriptan within 24 hours of each other; choose a single triptan per attack.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可解鎖 Frovatriptan 與 Rizatriptan 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
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常見問題

Can I take Frovatriptan with Rizatriptan?

MediHelp rates the interaction as contraindicated. Frovatriptan and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Frovatriptan and rizatriptan are both 5-HT1B/1D agonists that constrict cranial and coronary vessels. Taken close together, the vasoconstriction is additive and may cause coronary or peripheral vasospasm.

How serious is the interaction between Frovatriptan and Rizatriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use frovatriptan and rizatriptan within 24 hours of each other; choose a single triptan per attack.

What other medicines interact with Rizatriptan?

MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Rizatriptan page.

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