藥物交互作用
Febuxostat + Theophylline
嚴重程度: 中度
Febuxostat and Theophylline: moderate interaction.
最後更新
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摘要
Febuxostat inhibits xanthine oxidase, which contributes to theophylline metabolism to 1-methylxanthine, but studies show little effect on theophylline levels. A rise in metabolite is the main change.
用白話說明這項交互作用的意義
Febuxostat and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Febuxostat belongs to Genitourinary; Theophylline belongs to Respiratory.
為什麼會發生
Xanthine oxidase inhibition altering theophylline metabolites
處置方式
Monitor theophylline levels when starting febuxostat.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Theophylline 的其他交互作用
Febuxostat 的其他交互作用
常見問題
Can I take Febuxostat with Theophylline?
MediHelp rates the interaction as moderate. Febuxostat and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Febuxostat inhibits xanthine oxidase, which contributes to theophylline metabolism to 1-methylxanthine, but studies show little effect on theophylline levels. A rise in metabolite is the main change.
How serious is the interaction between Febuxostat and Theophylline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor theophylline levels when starting febuxostat.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
