藥物交互作用
Fondaparinux + Ketorolac
嚴重程度: 禁忌併用
Fondaparinux and Ketorolac: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Ketorolac impairs platelet function and can cause GI bleeding, while fondaparinux is a factor Xa inhibitor anticoagulant, so major bleeding risk increases. Ketorolac labeling contraindicates use in patients at risk of bleeding.
用白話說明這項交互作用的意義
Fondaparinux and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Fondaparinux belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
為什麼會發生
Additive hemostatic impairment from NSAID platelet inhibition and indirect factor Xa inhibition.
處置方式
Avoid ketorolac with fondaparinux and use a non-NSAID analgesic; if exposed, monitor for bleeding and hemoglobin.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ketorolac 的其他交互作用
Fondaparinux 的其他交互作用
常見問題
Can I take Fondaparinux with Ketorolac?
MediHelp rates the interaction as contraindicated. Fondaparinux and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac impairs platelet function and can cause GI bleeding, while fondaparinux is a factor Xa inhibitor anticoagulant, so major bleeding risk increases. Ketorolac labeling contraindicates use in patients at risk of bleeding.
How serious is the interaction between Fondaparinux and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac with fondaparinux and use a non-NSAID analgesic; if exposed, monitor for bleeding and hemoglobin.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
