藥物交互作用
Glyburide-metformin + Niacin
嚴重程度: 中度
Glyburide-metformin and Niacin: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Niacin at lipid-lowering doses raises blood glucose and may worsen control in diabetic patients. Dose adjustment of antidiabetic drugs is sometimes needed.
用白話說明這項交互作用的意義
Glyburide-metformin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glyburide-metformin belongs to Endocrine; Niacin belongs to Cardiovascular.
為什麼會發生
Niacin induces insulin resistance and increases hepatic glucose output, opposing antidiabetic effects.
處置方式
Monitor blood glucose and HbA1c after starting or increasing niacin. Increase antidiabetic therapy if control worsens.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glyburide-metformin 的其他交互作用
Niacin 的其他交互作用
常見問題
Can I take Glyburide-metformin with Niacin?
MediHelp rates the interaction as moderate. Glyburide-metformin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Niacin at lipid-lowering doses raises blood glucose and may worsen control in diabetic patients. Dose adjustment of antidiabetic drugs is sometimes needed.
How serious is the interaction between Glyburide-metformin and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting or increasing niacin. Increase antidiabetic therapy if control worsens.
What other medicines interact with Glyburide-metformin?
MediHelp also lists interactions of Glyburide-metformin with, for example, Bosentan, Cholic acid, Clarithromycin. The full list is on the Glyburide-metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
