藥物交互作用
Hydroxyurea + Mitoxantrone
嚴重程度: 嚴重
Hydroxyurea and Mitoxantrone: major interaction.
最後更新
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摘要
Both drugs suppress bone marrow, so combined use can deepen neutropenia, anemia and thrombocytopenia and raise infection and bleeding risk.
用白話說明這項交互作用的意義
Hydroxyurea and Mitoxantrone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Hydroxyurea belongs to Miscellaneous; Mitoxantrone belongs to Central Nervous System.
為什麼會發生
Additive myelosuppression.
處置方式
Monitor complete blood counts frequently and reduce doses or delay therapy for significant cytopenias.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Mitoxantrone 的其他交互作用
Hydroxyurea 的其他交互作用
常見問題
Can I take Hydroxyurea with Mitoxantrone?
MediHelp rates the interaction as major. Hydroxyurea and Mitoxantrone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs suppress bone marrow, so combined use can deepen neutropenia, anemia and thrombocytopenia and raise infection and bleeding risk.
How serious is the interaction between Hydroxyurea and Mitoxantrone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts frequently and reduce doses or delay therapy for significant cytopenias.
What other medicines interact with Mitoxantrone?
MediHelp also lists interactions of Mitoxantrone with, for example, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel, Belatacept. The full list is on the Mitoxantrone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
