藥物交互作用
Levothyroxine + Teduglutide
嚴重程度: 中度
Levothyroxine and Teduglutide: moderate interaction.
最後更新
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摘要
Teduglutide improves intestinal absorption of fluid and nutrients, which may increase absorption of oral levothyroxine. This could raise thyroid hormone exposure and cause signs of over-replacement in patients with short bowel syndrome.
用白話說明這項交互作用的意義
Levothyroxine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levothyroxine belongs to Endocrine; Teduglutide belongs to Endocrine.
為什麼會發生
Teduglutide has intestinotrophic effects that enhance gastrointestinal absorption of orally administered drugs.
處置方式
Monitor TSH and free T4 after starting teduglutide and after dose changes. Reduce the levothyroxine dose if over-replacement develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Levothyroxine 的其他交互作用
Teduglutide 的其他交互作用
常見問題
Can I take Levothyroxine with Teduglutide?
MediHelp rates the interaction as moderate. Levothyroxine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide improves intestinal absorption of fluid and nutrients, which may increase absorption of oral levothyroxine. This could raise thyroid hormone exposure and cause signs of over-replacement in patients with short bowel syndrome.
How serious is the interaction between Levothyroxine and Teduglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor TSH and free T4 after starting teduglutide and after dose changes. Reduce the levothyroxine dose if over-replacement develops.
What other medicines interact with Levothyroxine?
MediHelp also lists interactions of Levothyroxine with, for example, Cholestyramine, Sodium iodide i-131, Tiratricol. The full list is on the Levothyroxine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
