藥物交互作用
Manganese + Omadacycline
嚴重程度: 中度
Manganese and Omadacycline: moderate interaction.
最後更新
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摘要
Oral manganese can bind omadacycline in the gut and lower its absorption, which may reduce antibacterial efficacy.
用白話說明這項交互作用的意義
Manganese and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Manganese belongs to Gastrointestinal Tract; Omadacycline belongs to Anti Bacterial.
為什麼會發生
Multivalent cations chelate tetracyclines in the gastrointestinal tract, reducing absorption.
處置方式
Separate oral omadacycline from manganese-containing supplements by several hours, following labeling advice for tetracyclines and cations.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Manganese 的其他交互作用
Omadacycline 的其他交互作用
常見問題
Can I take Manganese with Omadacycline?
MediHelp rates the interaction as moderate. Manganese and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral manganese can bind omadacycline in the gut and lower its absorption, which may reduce antibacterial efficacy.
How serious is the interaction between Manganese and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate oral omadacycline from manganese-containing supplements by several hours, following labeling advice for tetracyclines and cations.
What other medicines interact with Manganese?
MediHelp also lists interactions of Manganese with, for example, Delafloxacin, Sarecycline, Baloxavir marboxil. The full list is on the Manganese page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
