藥物交互作用
Phenelzine + Phenylephrine
嚴重程度: 禁忌併用
Phenelzine and Phenylephrine: contraindicated interaction.
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摘要
Phenelzine is an irreversible MAO inhibitor, which can greatly amplify the pressor response to sympathomimetics. A hypertensive crisis may occur.
用白話說明這項交互作用的意義
Phenelzine and Phenylephrine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Phenelzine belongs to Central Nervous System; Phenylephrine belongs to Respiratory.
為什麼會發生
Inhibition of MAO increases availability of norepinephrine and enhances the pressor response to phenylephrine.
處置方式
Avoid systemic phenylephrine in patients taking MAO inhibitors, including for two weeks after stopping. Use a non-sympathomimetic decongestant alternative.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Phenylephrine 的其他交互作用
Phenelzine 的其他交互作用
常見問題
Can I take Phenelzine with Phenylephrine?
MediHelp rates the interaction as contraindicated. Phenelzine and Phenylephrine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Phenelzine is an irreversible MAO inhibitor, which can greatly amplify the pressor response to sympathomimetics. A hypertensive crisis may occur.
How serious is the interaction between Phenelzine and Phenylephrine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic phenylephrine in patients taking MAO inhibitors, including for two weeks after stopping. Use a non-sympathomimetic decongestant alternative.
What other medicines interact with Phenylephrine?
MediHelp also lists interactions of Phenylephrine with, for example, Isocarboxazid, Tranylcypromine, Bromocriptine. The full list is on the Phenylephrine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
