藥物交互作用
Dihydroergotamine + Phenylephrine
嚴重程度: 嚴重
Dihydroergotamine and Phenylephrine: major interaction.
最後更新
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摘要
Both drugs cause vasoconstriction, and together they can cause marked hypertension and peripheral or cerebral ischemia. The effect is most relevant with systemic phenylephrine.
用白話說明這項交互作用的意義
Dihydroergotamine and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dihydroergotamine belongs to Central Nervous System; Phenylephrine belongs to Respiratory.
為什麼會發生
Additive alpha-adrenergic and serotonergic vasoconstriction.
處置方式
Avoid systemic phenylephrine with dihydroergotamine. If unavoidable, monitor blood pressure and for signs of ischemia such as limb coldness or chest pain.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Phenylephrine 的其他交互作用
Dihydroergotamine 的其他交互作用
常見問題
Can I take Dihydroergotamine with Phenylephrine?
MediHelp rates the interaction as major. Dihydroergotamine and Phenylephrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs cause vasoconstriction, and together they can cause marked hypertension and peripheral or cerebral ischemia. The effect is most relevant with systemic phenylephrine.
How serious is the interaction between Dihydroergotamine and Phenylephrine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic phenylephrine with dihydroergotamine. If unavoidable, monitor blood pressure and for signs of ischemia such as limb coldness or chest pain.
What other medicines interact with Phenylephrine?
MediHelp also lists interactions of Phenylephrine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Phenylephrine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
