Diseases
ankylosing spondylitis
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Ankylosing spondylitis is an inflammatory disease that, over time, can cause some of the bones in the spine (vertebrae) to fuse. This fusing makes the spine less flexible and can result in a hunched posture. If ribs are affected, it can be difficult to breathe deeply.
Symptoms
- pain and stiffness in the lower back and hips ...
- the vertebrae in the lower back...
- the cartilage between the breastbone and the ribs...
- the hip and shoulder joints.
Causes
- ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. in particular, people who have a gene called hla-b27 are at a greatly increased risk of developing ankylosing spondylitis.
Risk factors
- men are more likely to develop ankylosing spondylitis than are women.
- most people who have ankylosing spondylitis have the hla-b27 gene.
Diagnosis
- imaging tests eg, (x-rays, mri)
- blood test(blood can be tested for the hla-b27 gene.).
Medicines used
Frequently asked questions
What is ankylosing spondylitis?
Ankylosing spondylitis is an inflammatory disease that, over time, can cause some of the bones in the spine (vertebrae) to fuse. This fusing makes the spine less flexible and can result in a hunched posture. If ribs are affected, it can be difficult to breathe deeply.
What are the symptoms of ankylosing spondylitis?
pain and stiffness in the lower back and hips ..., the vertebrae in the lower back..., the cartilage between the breastbone and the ribs..., the hip and shoulder joints.
What causes ankylosing spondylitis?
ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. in particular, people who have a gene called hla-b27 are at a greatly increased risk of developing ankylosing spondylitis.
Which medicines are used for ankylosing spondylitis?
aceclofenac, adalimumab, celecoxib, certolizumab pegol, diclofenac, etanercept, etoricoxib, golimumab, infliximab, ixekizumab, meclofenamic acid, naproxen, secukinumab, sulindac, tofacitinib, upadacitinib
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