Drug reference
probenecid
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Genitourinary (Anti Gout)
Mechanism of action
(Uricosuric) inhibits tubular reabsorption of urate; increasing uric acid excretion, Also inhibits tubular secretion of weak organic acids like PCNs & cephalosporins
Common side effects
- Vomiting
- Headache
- Nausea
- GI upset
- Loss of appetite
Contraindications
- Age <2 years Uric acid kidney stones, acute gouty arthritis Hypersensitivity Blood dyscrasias Administration during gouty attack Small or large dose aspirin therapy
Known interactions (1)
- furosemide + probenecid Moderate
Related conditions
Frequently asked questions
What drug class is probenecid?
probenecid belongs to: Genitourinary.
How does probenecid work?
(Uricosuric) inhibits tubular reabsorption of urate; increasing uric acid excretion, Also inhibits tubular secretion of weak organic acids like PCNs & cephalosporins
What are the common side effects of probenecid?
Vomiting, Headache, Nausea, GI upset, Loss of appetite
Which drugs interact with probenecid?
furosemide
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