Drug reference
dolutegravir
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Virals (Antiretroviral)
Mechanism of action
Integrase strand transfer inhibitor (INSTI); inhibits catalytic activity of HIV-1 integrase, an HIV encoded enzyme required for viral replication
Common side effects
- Increased cholesterol and triglycerides
- Hyperglycemia
- Increased lipase
- Increased creatinine kinase
Contraindications
- Documented hypersensitivity Coadministration with dofetilide due to the potential for increased dofetilide plasma concentrations and the risk for serious and/or life-threatening events
Known interactions (1)
- dolutegravir + rifampin Major
Related conditions
Frequently asked questions
What drug class is dolutegravir?
dolutegravir belongs to: Anti Virals.
How does dolutegravir work?
Integrase strand transfer inhibitor (INSTI); inhibits catalytic activity of HIV-1 integrase, an HIV encoded enzyme required for viral replication
What are the common side effects of dolutegravir?
Increased cholesterol and triglycerides, Hyperglycemia, Increased lipase, Increased creatinine kinase
Which drugs interact with dolutegravir?
rifampin
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.