Drug reference
rizatriptan
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Migraine Drugs)
Mechanism of action
Selective 5-HT1 receptor agonist in cranial arteries; causes vasoconstriction and reduces inflammation associated with antidromic neuronal transmission linked to relief of migraine
Common side effects
- Asthenia
- Dizziness
- Somnolence
- Drowsiness
- Fatigue
- Nausea
- Hot flashes
Known interactions (7)
- almotriptan + rizatriptan Contraindicated
- eletriptan + rizatriptan Contraindicated
- ergotamine + rizatriptan Contraindicated
- frovatriptan + rizatriptan Contraindicated
- isocarboxazid + rizatriptan Contraindicated
- Amitriptyline/Perphenazine + rizatriptan Moderate
- cabergoline + rizatriptan Moderate
Related conditions
Frequently asked questions
What drug class is rizatriptan?
rizatriptan belongs to: Central Nervous System.
How does rizatriptan work?
Selective 5-HT1 receptor agonist in cranial arteries; causes vasoconstriction and reduces inflammation associated with antidromic neuronal transmission linked to relief of migraine
What are the common side effects of rizatriptan?
Asthenia, Dizziness, Somnolence, Drowsiness, Fatigue, Nausea, Hot flashes
Which drugs interact with rizatriptan?
almotriptan, eletriptan, ergotamine, frovatriptan, isocarboxazid, Amitriptyline/Perphenazine, cabergoline
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