Drug interactions
Amikacin + Cefditoren
Severity: Minor
Amikacin and Cefditoren: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can affect the kidney, and amikacin also carries ototoxicity risk. Oral cefditoren has little nephrotoxic potential of its own, so any added risk is small, but renal impairment can raise amikacin levels and its toxicity.
What this interaction means in plain words
Amikacin and Cefditoren have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amikacin belongs to Anti Bacterial; Cefditoren belongs to Anti Bacterial.
Why it happens
Possible additive renal effects; aminoglycoside toxicity is concentration-dependent and worsens if renal clearance falls.
What to do
Monitor serum creatinine and amikacin levels, and adjust the amikacin dose to renal function. Ask about hearing or balance symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
Other interactions of Amikacin
- Amikacin + Cidofovir Contraindicated
- Adefovir + Amikacin Major
- Amikacin + Amphotericin b Major
- Amikacin + Amphotericin b deoxycholate Major
- Amikacin + Atracurium Major
- Amikacin + Bacitracin Major
Frequently asked questions
Can I take Amikacin with Cefditoren?
MediHelp rates the interaction as minor. Amikacin and Cefditoren have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can affect the kidney, and amikacin also carries ototoxicity risk. Oral cefditoren has little nephrotoxic potential of its own, so any added risk is small, but renal impairment can raise amikacin levels and its toxicity.
How serious is the interaction between Amikacin and Cefditoren?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin levels, and adjust the amikacin dose to renal function. Ask about hearing or balance symptoms.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
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