Drug interactions
Calcium + Cefditoren
Severity: Moderate
Calcium and Cefditoren: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefditoren absorption falls when gastric acidity is reduced by antacids or acid suppressants, and calcium carbonate can have this effect. Lower exposure may compromise antibacterial efficacy.
What this interaction means in plain words
Calcium and Cefditoren can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Cefditoren belongs to Anti Bacterial.
Why it happens
Raised gastric pH reduces the dissolution and absorption of cefditoren pivoxil.
What to do
Avoid concurrent dosing; give cefditoren at least 2 hours apart from calcium carbonate or choose another antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
- Cefditoren + Famotidine Moderate
Frequently asked questions
Can I take Calcium with Cefditoren?
MediHelp rates the interaction as moderate. Calcium and Cefditoren can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefditoren absorption falls when gastric acidity is reduced by antacids or acid suppressants, and calcium carbonate can have this effect. Lower exposure may compromise antibacterial efficacy.
How serious is the interaction between Calcium and Cefditoren?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent dosing; give cefditoren at least 2 hours apart from calcium carbonate or choose another antibiotic.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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